Compound file

Testosterone Replacement Therapy (TRT)

TRT is FDA-approved for treating male hypogonadism with well-established efficacy in restoring testosterone to physiological ranges (400-700 ng/dL). The landmark TRAVERSE trial (5,246 participants) confirmed cardiovascular safety in high-risk men. Intramuscular and subcutaneous testosterone esters provide sustained levels with predictable pharmacokinetics and documented improvements in energy, mood, libido, muscle mass, and bone density.